Clinical Stage Transitions in Persons Aged 12 to 25 Years Presenting to Early Intervention Mental Health Services With Anxiety, Mood, and Psychotic Disorders

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Mental disorders that commonly emerge during adolescence and young adulthood are associated with substantial immediate burden and risks, as well as potentially imparting lifetime morbidity and premature mortality.

This longitudinal cohort study of persons aged 12 to 25 years who presented to early intervention services found significant and ongoing risk of transition to major anxiety, mood, psychotic, or comorbid disorders. Poorer social function, psychotic-like experiences, manic-like experiences, and circadian disturbance were associated with illness progression.

Alex Wain